Alok Tripathi1, Surabhi Singhal1,
Navneet Sharma1
1.
Abstract
Allium sativum (Garlic) is considered as most significant herbs that have been used as traditional medicine from very old times. From ancient to current time different studies have confirmed the significant biological activities of garlic which includes anti-infectious properties, anti-inflammatory, antioxidant, anti-obesity, cardiovascular protective, anti-diabetic, free radical scavenging and anticancer properties.
Allium sativum has a diverse range of bioactive compounds and these are mainly organosulfur compounds, phenolic compounds and saponins. Primarily dominating phytochemicals are sulfur-containing compounds which are Alliin (C6H11NO3S), Allicin (C6H10OS2), E-Ajoene (C9H14OS3), Z-Ajoene (C9H14OS3), 2-Vinyl-4H-1,3-dithiin (C6H8S2), Diallyl sulfide (C6H10S), Diallyl disulfide (C6H10S2), Diallyl trisulfide (C6H10S3), Allyl methyl sulfide (C4H8S). It’s found that bioavailability of capsule prepared by garlic powder is in the range of 26-109 % while bioavailability of non enteric tablets is in the range of 80-111 %. It shows that bioavailability of tablets are more in comparison to capsule of garlic powder
Current review discusses the chemical bioactive compound compositions of the Allium sativum (Garlic) and its pharmacological properties, which prove the importance of garlic in the cure of different types of diseases.
Keywords: Garlic, Allium
Sativum, Antioxidant, Anti-inflammatory, Anticancer
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Publication
Article ID: P0301014 RA
Received: 03/03/2021
Accepted: 14/04/2021
Published: 30/09/2021
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How to cite this paper